Human 3-Galactosyl-N-Acetylglucosaminide 4-Alpha-L-Fucosyltransferase FUT3 (FUT3) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits FUT3
proveedor
Abbexareference
abx151599Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Fucosyltransferase 3 (FUT3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fucosyltransferase 3 (FUT3) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Fucosyltransferase 3 (FUT3)No significant cross-reactivity or interference between Fucosyltransferase 3 (FUT3) and analogues was observed.
Background
Fucosyltransferase 3 (FUT3) is an enzyme within the glycosyltransferase family that is essential for the biosynthesis of specific carbohydrate structures on glycoproteins and glycolipids. FUT3 is responsible for catalyzing the addition of fucose, a hexose sugar, to various glycan substrates through α(1,3)- and α(1,4)-linkages, which are critical for the synthesis of the Lewis antigen family, including Lewis a (Le^a) and Lewis b (Le^b) antigens. These carbohydrate structures are integral components of cell surface glycoconjugates and play essential roles in cell-cell adhesion, recognition, and signaling. Encoded by the FUT3 gene located on chromosome 19p13.3, FUT3 is primarily expressed in epithelial tissues and leukocytes, especially in the gastrointestinal tract and other mucosal tissues. It is one of several fucosyltransferases in the human genome, with FUT3 being the most involved in the generation of Lewis antigens. The genetic variations in FUT3 are known to result in different phenotypes of Lewis antigens, which are important in blood group determination and are relevant to various diseases, including cancers and inflammatory conditions.
Características del producto
category
ELISA Kits
immunogen target
3-Galactosyl-N-Acetylglucosaminide 4-Alpha-L-Fucosyltransferase FUT3 (FUT3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3,Lewis blood group,LE,Les,FT3B,CD174,FucT-III,Fucosyltransferase III
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FUT3
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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