Human Frizzled Homolog 9 (FZD9) ELISA Kit
715€ (96 tests)
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name
Human Frizzled Homolog 9 (FZD9) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx259577
tested applications
ELISA
Description
Human Frizzled Homolog 9 (FZD9) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Frizzled Homolog 9 (FZD9) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Frizzled Homolog 9 (FZD9) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O00144 |
| Gene ID | 8326 |
| OMIM | 601766 |
| Alias | FZD9,FZD3,CD349,frizzled family receptor 9 |
| Background | Elisa kits for FZD9 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FZD9 is a member of the Frizzled family of G protein-coupled receptors involved in Wnt signaling, primarily through the canonical β-catenin-dependent pathway. It is highly expressed in the brain, spleen, and bone, where it plays critical roles in neuronal development, immune regulation, and bone homeostasis. In bone biology, FZD9 promotes osteoblast differentiation and mineralization, contributing to skeletal development and bone repair. Deletion or reduced expression of FZD9 is associated with bone fragility and osteoporosis, highlighting its importance in bone formation. In the central nervous system, FZD9 regulates neural connectivity, synaptic plasticity, and cognitive function, with its dysregulation linked to neurodevelopmental disorders and neurodegenerative diseases like Alzheimer’s. FZD9 also contributes to immune system function, particularly in lymphocyte development and maturation. In cancer, FZD9 expression is altered in B-cell malignancies, such as multiple myeloma, where it influences cell proliferation and survival through Wnt signaling activation. FZD9’s role in maintaining tissue homeostasis and its dysregulation in bone disease and cancer make it a potential therapeutic target for osteoporosis and hematological malignancies.
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