Human Frizzled Homolog 3 (FZD3) ELISA Kit
715€ (96 tests)
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name
Human Frizzled Homolog 3 (FZD3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx250521
tested applications
ELISA
Description
Human Frizzled Homolog 3 (FZD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Frizzled Homolog 3 (FZD3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Frizzled Homolog 3 (FZD3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9NPG1 |
| Alias | FZD3,Fz3,frizzled 3,frizzled family receptor 3,Fz-3 |
| Background | Elisa kits for FZD3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FZD3 is a member of the Frizzled family involved primarily in non-canonical Wnt signaling pathways, including planar cell polarity (PCP) and Wnt/Ca2+ signaling. It is highly expressed in the nervous system, particularly during embryonic development, where it regulates axon guidance, neural crest cell migration, and synapse formation. FZD3 is critical for establishing cellular polarity, neural connectivity, and patterning during brain and spinal cord development. In the peripheral nervous system, it directs the migration of neural crest-derived cells and the growth of sensory and motor neurons. Dysregulation of FZD3 has been linked to neurodevelopmental disorders, such as defective axonal outgrowth and neuronal wiring defects. In cancer, FZD3 is implicated in promoting cell migration, invasion, and metastasis in certain cancers, including breast and colorectal cancers, through its role in non-canonical signaling. FZD3’s contribution to axonal regeneration and neural plasticity makes it a potential target for treating neurological injuries and neurodegenerative diseases. Overall, FZD3 is essential for neural development, cellular polarity, and migration, balancing normal development with disease pathology.
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