Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit

Este producto es parte de FCGR2A - Fc gamma receptor Iia
Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit
689€ (96 tests)

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Name
Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx151502
Tested Applications
ELISA

Description

Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Receptor II For The Fc Region Of Immunoglobulin G (FcgRII)

Documentos del producto

Instrucciones
Descargar
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
46.9 pg/ml - 3000 pg/ml
Sensitivity
< 17.4 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
CD32,FCG2,FcGR,CD32A,CDw32,FCGR2,IGFR2,FCGR2A,FcgammaRIIa,Low affinity immunoglobulin gamma Fc region receptor II-a,IgG Fc receptor II-a,Fc-gamma RII-a
Background
Elisa Kits for: FCGR2A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

FCGR2A (Fc gamma receptor IIa), also known as CD32a, is a low-affinity receptor for the Fc region of immunoglobulin G (IgG). It plays a crucial role in immune regulation by mediating various cellular responses, including phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and the clearance of immune complexes. FCGR2A is part of a larger family of Fc gamma receptors (FcγRs), which are responsible for bridging adaptive and innate immunity by recognizing the Fc region of IgG and triggering effector cell responses. FcγR family members, including FCGR2A, are broadly expressed on the surface of various immune cells such as monocytes, macrophages, neutrophils, dendritic cells, and platelets. FCGR2A is unique among Fc receptors because of its capacity to mediate both activating and inhibitory immune responses, depending on the cellular context and signaling pathways involved.

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