Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit

Este producto es parte de FCGR2A - Fc gamma receptor Iia
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689€ (96 tests)

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935106861
info@markelab.com
name
Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx151502
tested applications
ELISA

Description

Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Receptor II For The Fc Region Of Immunoglobulin G (FcgRII)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetFc Fragment of IgG, Low Affinity IIa, Receptor / CD32 (FCGR2A)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range46.9 pg/ml - 3000 pg/ml
Sensitivity< 17.4 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasCD32,FCG2,FcGR,CD32A,CDw32,FCGR2,IGFR2,FCGR2A,FcgammaRIIa,Low affinity immunoglobulin gamma Fc region receptor II-a,IgG Fc receptor II-a,Fc-gamma RII-a
BackgroundElisa kits for FCGR2A
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

FCGR2A (Fc gamma receptor IIa), also known as CD32a, is a low-affinity receptor for the Fc region of immunoglobulin G (IgG). It plays a crucial role in immune regulation by mediating various cellular responses, including phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and the clearance of immune complexes. FCGR2A is part of a larger family of Fc gamma receptors (FcγRs), which are responsible for bridging adaptive and innate immunity by recognizing the Fc region of IgG and triggering effector cell responses. FcγR family members, including FCGR2A, are broadly expressed on the surface of various immune cells such as monocytes, macrophages, neutrophils, dendritic cells, and platelets. FCGR2A is unique among Fc receptors because of its capacity to mediate both activating and inhibitory immune responses, depending on the cellular context and signaling pathways involved.

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