Human Disrupted in Schizophrenia 1 Protein (DISC1) ELISA Kit

Este producto es parte de DISC1 Scaffold Protein
Human Disrupted in Schizophrenia 1 Protein (DISC1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DISC1

proveedor

Abbexa

reference

abx384805

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Disrupted in Schizophrenia 1 Protein (DISC1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DISC1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Disrupted in schizophrenia 1 (DISC1) is a scaffolding protein with diverse roles in neurodevelopment, synaptic function, and adult neurogenesis. Originally identified in a Scottish family with a high incidence of schizophrenia, DISC1 has since been implicated in several psychiatric disorders, including bipolar disorder and major depression. DISC1 interacts with multiple molecular partners, influencing signaling pathways involved in neuronal proliferation, migration, and axonal growth. Additionally, it regulates mitochondrial function and intracellular trafficking. Dysfunctional DISC1 has been associated with structural brain abnormalities, synaptic deficits, and altered neuronal connectivity, which are common features in neuropsychiatric disorders. The multifaceted roles of DISC1 in cellular processes and its potential as a biomarker or therapeutic target underscore its significance in neuroscience and psychiatry research.

Características del producto

category

ELISA Kits


immunogen target

Disrupted in Schizophrenia 1 Protein (DISC1)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.13 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DISC1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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