Human Desmoglein-1 (DSG1) Protein
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Description
Human Desmoglein-1 (DSG1) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Desmoglein-1 (DSG1) |
| Host | Mammalian cells |
| Assay Type | Activity: Not tested Sequence Fragment: Glu50-Pro548 Tag: C-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 58.56 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% Trehalose, 5% Mannitol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q02413 |
| Background | Protein DSG1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile water to produce a stock solution. Concentration: Prior to lyophilization: 0.38 mg/ml |
Descripción
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DSG1 antibody
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
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