Human Delta-Like Protein 4 (DLL4) Protein
546€ (100 µg)
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935106861
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name
Human Delta-Like Protein 4 (DLL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620616
tested applications
ELISA, WB, SDS-PAGE
Description
Human Delta-Like Protein 4 (DLL4) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Delta-Like Protein 4 (DLL4) |
| Host | Mammalian cells |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 92.04 kDa Sequence Fragment: Met1-Trp529 Tag: C-terminal Fc-His-Avi tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized Reconstitute in sterile water to produce a stock solution. |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NR61 |
| Background | Protein DLL4 |
| Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
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