Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit
715€ (96 tests)
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Name
Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx386964
Tested Applications
ELISA
Description
Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOCK7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Dedicator Of Cytokinesis Protein 7 (DOCK7) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96N67 |
| Gene ID | 85440 |
| OMIM | 615730 |
| Alias | DEE23, EIEE23, ZIR2,KIAA1771 |
| Background | Elisa Kits for: DOCK7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
DOCK7 is a GEF for Rac1 and Cdc42, playing a key role in axon formation, neuronal polarization, and Schwann cell myelination. It regulates actin cytoskeleton dynamics and microtubule stabilization in neurons. DOCK7 interacts with the WAVE complex to promote Rac1-mediated actin remodeling, essential for neuronal growth and cortical development. It also regulates cell cycle progression in neural progenitors and is involved in epithelial-to-mesenchymal transition (EMT) in cancer. DOCK7 dysregulation is linked to neurological disorders and tumor progression. Mouse models with DOCK7 loss exhibit defects in neural development, including axonal growth and Schwann cell function.
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