Human Cytoplasmic protein NCK2 (NCK2) ELISA Kit

Este producto es parte de NCK adaptor protein
Human Cytoplasmic protein NCK2 (NCK2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NCK2

proveedor

Abbexa

reference

abx534661

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Cytoplasmic protein NCK2 (NCK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cytoplasmic protein NCK2 (NCK2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

NCK2, also called Grb4, is a close homolog of NCK1 and functions as an adaptor protein linking receptor tyrosine kinases (RTKs) and cytoplasmic signaling molecules. It contains three SH3 domains and one SH2 domain, enabling it to interact with proteins involved in actin cytoskeletal regulation, cell adhesion, and migration. NCK2 mediates signaling pathways that regulate cell growth, differentiation, and survival, particularly through interactions with proteins like WASP, WAVE, and PAK kinases. It has specialized roles in embryonic development, angiogenesis, and neuronal growth. Dysregulation of NCK2 is implicated in cancer, where it promotes migration and invasion through actin remodeling. Knockout models show impaired embryonic development, angiogenesis defects, and abnormalities in cell motility, underscoring its critical role in cytoskeletal dynamics and signal transduction.

Características del producto

category

ELISA Kits


immunogen target

Cytoplasmic protein NCK2 (NCK2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

NCK2, GRB4, NCKbeta, NCK adaptor protein 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NCK2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- NCK2 antibody

anti- NCK2 antibody

proveedor

FineTest

reference

FNab05584

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 dom...

Precio a consultar

Ver más

Recombinant Human Nck-2

Recombinant Human Nck-2

proveedor

FineTest

reference

P4169

Tested Applications

Western Blot,ELISA

status

RUO

Precio a consultar

Ver más

NCK Adaptor Protein 2 (NCK2) Antibody

NCK Adaptor Protein 2 (NCK2) Antibody

proveedor

Abbexa

reference

abx007051

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

NCK2 Antibody is a Rabbit Polyclonal Antibody against NCK2.

195€ (20 µl)

Ver más