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Human CTSB(Cathepsin B) ELISA Kit
proveedor
FineTestreference
EH0051Tested Applications
reactivity
humanstatus
RUOclonality
Background
The CTSB gene is located on chromosome 8p22 and encodes the enzyme cathepsin B, which belongs to the cathepsin group of lysosomal cysteine peptidases. Cathepsin B exhibits broad endopeptidase and peptidyl dipeptidase activity, with specific substrates like Z-Arg-Arg-methylcoumarylamide and similar dibasic compounds. An structural feature of cathepsin B is the presence of an 18-residue insertion known as the occluding loop. This enzyme is involved in various physiological and pathological processes, including apoptosis, tumor growth, metastasis, and pancreatitis.
Background
El gen CTSB está situado en el cromosoma 8p22 y codifica la enzima catepsina B, que pertenece al grupo de las peptidasas lisosomales. La catepsina B exhibe una amplia actividad de endopeptidasa y peptidil dipeptidasa, con sustratos específicos como Z-Arg-Arg-metilcumarilamida y compuestos dibásicos similares. Una característica estructural de la catepsina B es la presencia de una inserción de 18 residuos conocida como bucle de oclusión. Esta enzima participa en diversos procesos fisiológicos y patológicos, incluida la apoptosis, el crecimiento tumoral, la metástasis y la pancreatitis.
Características del producto
category
ELISA Kits
reactivity
human
test range
0.156-10ng/ml
assay type
Sandwich ELISA, Double Antibody
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96T
alias
CTSB|Cathepsin B|APPS|CPSB
storage
2-8 °C for 6 months
or code
CTSB
uniprot id
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