Human CTSB(Cathepsin B) ELISA Kit

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935106861

info@markelab.com

Precio

Precio a consultar

proveedor

FineTest

reference

EH0051

Tested Applications

reactivity

human

status

RUO

clonality

Background

The CTSB gene is located on chromosome 8p22 and encodes the enzyme cathepsin B, which belongs to the cathepsin group of lysosomal cysteine peptidases. Cathepsin B exhibits broad endopeptidase and peptidyl dipeptidase activity, with specific substrates like Z-Arg-Arg-methylcoumarylamide and similar dibasic compounds. An structural feature of cathepsin B is the presence of an 18-residue insertion known as the occluding loop. This enzyme is involved in various physiological and pathological processes, including apoptosis, tumor growth, metastasis, and pancreatitis.


El gen CTSB está situado en el cromosoma 8p22 y codifica la enzima catepsina B, que pertenece al grupo de las peptidasas lisosomales. La catepsina B exhibe una amplia actividad de endopeptidasa y peptidil dipeptidasa, con sustratos específicos como Z-Arg-Arg-metilcumarilamida y compuestos dibásicos similares. Una característica estructural de la catepsina B es la presencia de una inserción de 18 residuos conocida como bucle de oclusión. Esta enzima participa en diversos procesos fisiológicos y patológicos, incluida la apoptosis, el crecimiento tumoral, la metástasis y la pancreatitis.

Características del producto

category

ELISA Kits


size 1

96T


storage

2-8 °C for 6 months


uniprot id

P07858


test range

0.156-10ng/ml


detection method

Colorimetric


assay type

Sandwich ELISA, Double Antibody


assay data

Quantitative


availability

Shipped within 10-14 working days.


alias

CTSB|Cathepsin B|APPS|CPSB


short name

CTSB


status

RUO


sample type

Serum,Plasma,Tissue homogenates,Other biological fluids


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