Human Complement C3b (C3b) Protein
715€ (100 µg)
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Name
Human Complement C3b (C3b) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx670024
Tested Applications
ELISA
Description
Human Complement 3b Protein is a Native protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Complement C3b (C3b) |
| Host | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 180 kDa |
| Purity | >90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Phosphate buffered saline |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | Yes |
| UniProt ID | P01024 |
| Alias | ASP,C3a,C3b,AHUS5,ARMD9,CPAMD1,HEL-S-62p,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| Background | Protein C3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. This product is shipped with dry ice. Concentration: 1.0 mg/ml |
Background
Complement C3 is a central component of the complement system, an essential part of the innate immune response that aids in the clearance of pathogens and the regulation of inflammation C3 is involved in all three complement pathways (classical, alternative, and lectin), playing a critical role in immune defense by promoting opsonization, cell lysis, and inflammation activation Upon cleavage into C3a and C3b, C3a acts as an inflammatory mediator, and C3b binds to pathogens to mark them for destruction by phagocytes Complement C3 deficiency or dysfunction is associated with various autoimmune diseases, such as systemic lupus erythematosus (SLE), and with susceptibility to infections C3 is also involved in the regulation of adaptive immunity, influencing antibody production and T-cell responses Its role in inflammation, pathogen clearance, and immune system regulation highlights its importance in maintaining immune balance and tissue homeostasis
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