Human Complement C4-B (C4B) ELISA Kit
689€ (96 tests)
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935106861
info@markelab.com
name
Human Complement C4-B (C4B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150865
tested applications
ELISA
Description
Human Complement C4-B (C4B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Complement C4-B (C4B) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Complement Complement C4b
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Complement C4-B (C4B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 4.7 ng/ml - 300 ng/ml |
| Sensitivity | < 1.9 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P0C0L5 |
| Gene ID | 721 |
| OMIM | 120820 |
| Alias | CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 |
| Background | Elisa kits for C4B |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation
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