Human Cluster of Differentiation 99 (CD99) ELISA Kit
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935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for CD99
proveedor
Abbexareference
abx253436Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Cluster of Differentiation 99 (CD99) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cluster of Differentiation 99 (CD99) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD99, also known as MIC2, is a cell surface glycoprotein expressed on various cell types, including leukocytes, endothelial cells, and certain tumor cells. The CD99 protein plays a role in multiple biological processes, such as cell adhesion, migration, apoptosis, and immune regulation. CD99 expression is crucial in thymocyte differentiation and T cell activation, as well as in leukocyte extravasation, where immune cells move from blood vessels to sites of inflammation. It is also involved in neural cell adhesion and spermatogenesis, highlighting its diverse functional roles across cell types and tissues. CD99 has garnered attention for its clinical implications, especially in cancer, as it is overexpressed in Ewing sarcoma and other tumors, making it a biomarker of diagnostic and therapeutic interest. Additionally, CD99 is involved in the immune response, where it contributes to the regulation of leukocyte activity and inflammation. The molecule also plays a role in apoptosis, promoting cell death in specific contexts, and has a dual role in tumor biology, both enhancing and inhibiting tumor progression depending on the cancer type and tissue context.
Características del producto
category
ELISA Kits
immunogen target
Cluster of Differentiation 99 (CD99)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Xg blood group,MIC2,HBA71,MIC2X,MIC2Y,MSK5X,Protein MIC2,T-cell surface glycoprotein E2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD99
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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