Human Cd82 Antigen (CD82) Protein

Este producto es parte de CD82 - CD82 molecule
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975€ (50 µg)

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935106861
info@markelab.com
name
Human Cd82 Antigen (CD82) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692326
tested applications
SDS-PAGE

Description

Cd82 Antigen (CD82) protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Cd82 Antigen (CD82)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Gly111-Leu228
Tag: C-terminal His tag
Origin
Human
Observed MW
15 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
50 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: Sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
P27701-1
Alias
R2,4F9,C33,IA4,ST6,GR15,KAI1,SAR2,TSPAN27,CD82 antigen,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27
Background
Protein CD82
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

CD82, also known as KAI1 (Kangai 1), is a member of the tetraspanin family, a group of integral membrane proteins involved in the regulation of cell development, motility, adhesion, and immune responses. CD82 is of particular interest in cancer biology due to its role as a metastasis suppressor gene. It was initially identified as a tumor suppressor in prostate cancer, and subsequent studies have demonstrated that it plays a significant role in suppressing metastasis across a range of cancers. The CD82 gene is located on chromosome 11p11.2 and is ubiquitously expressed in various cell types, including epithelial cells, immune cells, and neurons. The primary function of CD82 is to regulate cell-cell interactions and modulate signal transduction pathways. Importantly, CD82 is involved in the regulation of immune cell activation, adhesion, and migration, making it a vital component in both immune responses and cancer progression.

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