Human Cluster of Differentiation 160 (CD160) CLIA Kit

Este producto es parte de CD160 - CD160 molecule
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Cluster of Differentiation 160 (CD160) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492301
tested applications
CLIA

Description

Human Cluster Of Differentiation 160 (CD160) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetCluster of Differentiation 160 (CD160)
ReactivityHuman
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range78.12 pg/ml - 5000 pg/ml
Sensitivity< 30 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeSerum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
AvailabilityShipped within 5-20 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasNK1,BY55,NK28,Natural killer cell receptor BY55
BackgroundCLIA Kits CD160
StatusRUO
NoteThe validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

The CD160 molecule, encoded by the CD160 gene, is a glycoprotein primarily expressed on the surface of cytotoxic lymphocytes, including natural killer (NK) cells, NKT cells, a subset of CD8+ T cells, and certain peripheral blood T-cell populations. CD160 was first identified for its unique expression pattern on immune cells and its role in modulating cytotoxic activity, playing a critical role in immune response against tumors and infected cells. CD160 functions as a receptor that binds to a variety of ligands, notably major histocompatibility complex (MHC) class I molecules and herpesvirus entry mediator (HVEM), both of which have implications in immune activation and inhibition. CD160 serves as an immune checkpoint, similar to other co-inhibitory receptors such as CTLA-4 and PD-1, and its signaling is implicated in modulating immune responses. Its functions in immune surveillance and regulation make it particularly significant in oncology, viral immunology, and autoimmune disorders. CD160 is also characterized by its restricted expression on peripheral blood monocytes and on cells in the gastrointestinal tract, indicating its broader role in tissue-specific immune responses and homeostasis.

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