Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein

Este producto es parte de CIDEA - Cell death inducing DFFA like effector A
Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein
234€ (10 µg)

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Name
Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx168285
Tested Applications
WB, SDS-PAGE

Description

Human Cell Death Inducing DFFA Like Effector A Protein is a recombinant Human protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Cell Death Inducing DFFA Like Effector A (CIDEA)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Met1-Gly219
Tag: N-terminal His tag and GST tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 57.1 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
O60543
Alias
CIDE-A, cell death-inducing DFFA-like effector a, cell death inducing DFFA like effector a,CIDEA
Background
Protein CIDEA
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

CIDEA is a lipid droplet-associated protein involved in regulating lipid metabolism and energy homeostasis. It promotes lipid droplet fusion and inhibits lipolysis by modulating the activity of key enzymes such as adipose triglyceride lipase (ATGL). CIDEA is highly expressed in brown adipose tissue, where it contributes to thermogenesis and energy expenditure. Beyond its metabolic functions, CIDEA also plays a role in apoptosis, where it interacts with caspase-activated DNAse to mediate DNA fragmentation. Dysregulation of CIDEA is associated with obesity, insulin resistance, and non-alcoholic fatty liver disease. Research on CIDEA focuses on its dual roles in lipid metabolism and apoptosis, offering potential therapeutic targets for metabolic disorders and cancer.

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