Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein CIDEA
proveedor
Abbexareference
abx168285Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Cell Death Inducing DFFA Like Effector A Protein is a recombinant Human protein expressed in E. coli.
Background
CIDEA is a lipid droplet-associated protein involved in regulating lipid metabolism and energy homeostasis. It promotes lipid droplet fusion and inhibits lipolysis by modulating the activity of key enzymes such as adipose triglyceride lipase (ATGL). CIDEA is highly expressed in brown adipose tissue, where it contributes to thermogenesis and energy expenditure. Beyond its metabolic functions, CIDEA also plays a role in apoptosis, where it interacts with caspase-activated DNAse to mediate DNA fragmentation. Dysregulation of CIDEA is associated with obesity, insulin resistance, and non-alcoholic fatty liver disease. Research on CIDEA focuses on its dual roles in lipid metabolism and apoptosis, offering potential therapeutic targets for metabolic disorders and cancer.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Cell Death Inducing DFFA Like Effector A (CIDEA)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 57.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Gly219 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CIDEA
dry ice
No
availability
Shipped within 5-7 working days.
alias
CIDE-A, cell death-inducing DFFA-like effector a, cell death inducing DFFA like effector a,CIDEA
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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