Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein

Este producto es parte de CIDEA - Cell death inducing DFFA like effector A
Human Cell Death Inducing DFFA Like Effector A (CIDEA) Protein

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935106861

info@markelab.com

Precio

234€ (10 µg)

Protein CIDEA

proveedor

Abbexa

reference

abx168285

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Cell Death Inducing DFFA Like Effector A Protein is a recombinant Human protein expressed in E. coli.


Background

CIDEA is a lipid droplet-associated protein involved in regulating lipid metabolism and energy homeostasis. It promotes lipid droplet fusion and inhibits lipolysis by modulating the activity of key enzymes such as adipose triglyceride lipase (ATGL). CIDEA is highly expressed in brown adipose tissue, where it contributes to thermogenesis and energy expenditure. Beyond its metabolic functions, CIDEA also plays a role in apoptosis, where it interacts with caspase-activated DNAse to mediate DNA fragmentation. Dysregulation of CIDEA is associated with obesity, insulin resistance, and non-alcoholic fatty liver disease. Research on CIDEA focuses on its dual roles in lipid metabolism and apoptosis, offering potential therapeutic targets for metabolic disorders and cancer.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Cell Death Inducing DFFA Like Effector A (CIDEA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 57.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Gly219 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CIDEA


dry ice

No


availability

Shipped within 5-7 working days.


alias

CIDE-A, cell death-inducing DFFA-like effector a, cell death inducing DFFA like effector a,CIDEA


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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