Human CD180 antigen (CD180) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human CD180 antigen (CD180) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx505728
tested applications
ELISA
Description
Human CD180 antigen (CD180) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human CD180 antigen (CD180) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | CD180 antigen (CD180) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q99467 |
| Alias | LY64,Ly78,RP105,Lymphocyte antigen 64,Radioprotective 105 kDa protein |
| Background | Elisa kits for CD180 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD180, also known as RP105 (radioprotective 105 kDa protein), is a cell surface molecule prominently expressed on immune cells, particularly B cells, macrophages, and dendritic cells. As a member of the Toll-like receptor (TLR) family, CD180 plays a significant role in the immune system by recognizing microbial components and activating immune responses. Although structurally similar to TLRs, CD180 functions distinctly by forming complexes with other receptors rather than directly recognizing pathogen-associated molecular patterns (PAMPs). Its primary function is to regulate B cell activation, proliferation, and differentiation, which is crucial for antibody production and adaptive immunity. CD180 is a regulatory receptor that modulates the response of B cells to various antigens, providing an essential checkpoint in immune activation to avoid excessive immune responses and maintain balance.
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