Human Caspase Recruitment Domain-Containing Protein 8 (CARD8) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CARD8
proveedor
Abbexareference
abx386296Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Caspase Recruitment Domain-Containing Protein 8 (CARD8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Caspase Recruitment Domain Family, Member 8 (CARD8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CARD8 is another member of the CARD protein family, involved in immune response regulation, particularly in the activation of inflammatory pathways. It contains a caspase recruitment domain (CARD), which is crucial for its role in signal transduction. CARD8 is involved in the regulation of the inflammasome, a complex that mediates the activation of caspase-1, leading to the production of pro-inflammatory cytokines such as IL-1β and IL-18. This protein is particularly important for detecting pathogens and cellular damage, promoting an appropriate inflammatory response. However, CARD8 can also regulate immune responses to prevent excessive inflammation, which is implicated in various chronic inflammatory diseases and autoimmune conditions. Research into CARD8 focuses on its role in diseases such as inflammatory bowel disease (IBD) and rheumatoid arthritis, where abnormal inflammasome activation is observed.
Características del producto
category
ELISA Kits
immunogen target
Caspase Recruitment Domain-Containing Protein 8 (CARD8)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
CARDINAL,DACAR,DAKAR,NDPP,NDPP1,TUCAN,CARD-inhibitor of NF-kappa-B-activating ligand
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CARD8
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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