Human Caspase Recruitment Domain-Containing Protein 8 (CARD8) ELISA Kit

Este producto es parte de CARD - Caspase recruitment domain-containing protein
Human Caspase Recruitment Domain-Containing Protein 8 (CARD8) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for CARD8

proveedor

Abbexa

reference

abx386296

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Caspase Recruitment Domain-Containing Protein 8 (CARD8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Caspase Recruitment Domain Family, Member 8 (CARD8) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

CARD8 is another member of the CARD protein family, involved in immune response regulation, particularly in the activation of inflammatory pathways. It contains a caspase recruitment domain (CARD), which is crucial for its role in signal transduction. CARD8 is involved in the regulation of the inflammasome, a complex that mediates the activation of caspase-1, leading to the production of pro-inflammatory cytokines such as IL-1β and IL-18. This protein is particularly important for detecting pathogens and cellular damage, promoting an appropriate inflammatory response. However, CARD8 can also regulate immune responses to prevent excessive inflammation, which is implicated in various chronic inflammatory diseases and autoimmune conditions. Research into CARD8 focuses on its role in diseases such as inflammatory bowel disease (IBD) and rheumatoid arthritis, where abnormal inflammasome activation is observed.

Características del producto

category

ELISA Kits


immunogen target

Caspase Recruitment Domain-Containing Protein 8 (CARD8)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

CARDINAL,DACAR,DAKAR,NDPP,NDPP1,TUCAN,CARD-inhibitor of NF-kappa-B-activating ligand


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

CARD8


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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