Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx386294
tested applications
ELISA
Description
Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Caspase Recruitment Domain-Containing Protein 14 (CARD14) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BXL6 |
| Gene ID | 79092 |
| OMIM | 173200 |
| Alias | CARD14,BIMP2, CARMA2, PRP, PSORS2, PSS1,CARD-containing MAGUK protein 2 |
| Background | Elisa kits for CARD14 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CARD14, also known as CARMA2 (Caspase Recruitment Domain-Containing Membrane-Associated Protein 2), is a protein that plays an important role in immune cell signaling, especially in the activation of NF-κB and other inflammatory pathways. It acts as an adaptor protein in the NF-κB signaling cascade, which is crucial for the immune response to pathogens. CARD14 is involved in various immune system functions, including the regulation of cytokine production and the activation of immune cells in response to infection. Recent studies have shown that CARD14 mutations are associated with psoriasis, an autoimmune skin disorder, suggesting that its regulation of immune responses is vital for maintaining immune system balance. Inappropriate activation or suppression of CARD14 may lead to the development of chronic inflammatory diseases, making it a potential target for therapeutic interventions in conditions such as psoriasis and other immune-related diseases.
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