Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CARD14
proveedor
Abbexareference
abx386294Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Caspase Recruitment Domain-Containing Protein 14 (CARD14) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CARD14, also known as CARMA2 (Caspase Recruitment Domain-Containing Membrane-Associated Protein 2), is a protein that plays an important role in immune cell signaling, especially in the activation of NF-κB and other inflammatory pathways. It acts as an adaptor protein in the NF-κB signaling cascade, which is crucial for the immune response to pathogens. CARD14 is involved in various immune system functions, including the regulation of cytokine production and the activation of immune cells in response to infection. Recent studies have shown that CARD14 mutations are associated with psoriasis, an autoimmune skin disorder, suggesting that its regulation of immune responses is vital for maintaining immune system balance. Inappropriate activation or suppression of CARD14 may lead to the development of chronic inflammatory diseases, making it a potential target for therapeutic interventions in conditions such as psoriasis and other immune-related diseases.
Características del producto
category
ELISA Kits
immunogen target
Caspase Recruitment Domain-Containing Protein 14 (CARD14)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CARD14,BIMP2, CARMA2, PRP, PSORS2, PSS1,CARD-containing MAGUK protein 2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CARD14
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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