Human Casein kinase I isoform gamma-2 (CSNK1G2) Protein
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Description
Human Casein kinase I isoform gamma-2 Protein is a recombinant protein from Human produced in E. coli. Recombinant Human Casein kinase I isoform gamma-2 is produced by our E.coli expression system and the target gene encoding Met18-Lys415 is expressed with a 6His tag at the N-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Casein kinase I isoform gamma-2 |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 47.6 kDa Sequence Fragment: Met18-Lys415 Tag: N-terminal 6 His tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM Tris, 500mM NaCl, 10%Glycerol, 1mM DTT, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at < -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78368-1 |
| Background | Protein CSNK1G2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).
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