Human Casein Kinase 1 gamma 2 (CSNK1G2) Protein (Active)
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Description
Human Casein Kinase 1 gamma 2 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the mature form of human CSNK1G2 (P78368-1) (Met 18-Lys 415) was expressed, with a polyhistidine tag at the N-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Casein Kinase 1 gamma 2 |
| Host | Insect |
| Origin | Human |
| Observed MW | Molecular Weight: 47.8 kDa Sequence Fragment: Met18-Lys415 Tag: N-terminal His tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 80% (SDS-PAGE) |
| Size 1 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | Supplied as sterile 20mM Tris, 500mM NaCl, 10% gly, 1mM DTT, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78368-1 |
| Background | Protein CSNK1G2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).
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