Human Troponin T, Cardiac Muscle (TNNT2) Protein
208€ (10 µg)
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935106861
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name
Human Troponin T, Cardiac Muscle (TNNT2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167122
tested applications
WB, SDS-PAGE
Description
Human Troponin T, Cardiac Muscle (TNNT2) Protein is a recombinant Human protein expressed in E. coli. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Troponin T, Cardiac Muscle (TNNT2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Lys295 Tag: N-terminal His and GST tags |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 65.6 kDa Observed MW (SDS-PAGE): 70 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P45379 |
| Gene ID | 7139 |
| NCBI Accession | NP_001001432.1, NM_001001432.2 |
| OMIM | 115195 |
| Background | Protein TNNT2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
