Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Protein

Este producto es parte de CEACAM6 - CEA cell adhesion molecule 6
Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein CEACAM6

proveedor

Abbexa

reference

abx166856

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 Protein is a recombinant Human protein expressed in E. coli.


Background

CEACAM6, also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which belong to the larger immunoglobulin superfamily (IgSF). CEACAM6 is a glycoprotein primarily involved in intercellular adhesion, immune response modulation, and tumor progression. It is expressed on the surface of various cell types, particularly epithelial cells, granulocytes, and certain cancer cells. CEACAM6, like other CEACAM family members, plays a key role in cellular interactions and communication. In addition to its normal physiological roles in cell adhesion, CEACAM6 is implicated in tumorigenesis, especially in cancers like colorectal, pancreatic, lung, and breast cancer. CEACAM6 is often overexpressed in these malignancies, contributing to tumor growth, metastasis, and resistance to apoptosis. Its expression in the immune system and epithelial cells also means it has important functions in immune modulation and maintaining the integrity of epithelial barriers.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 15.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys35-Pro142 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CEACAM6


dry ice

No


availability

Shipped within 5-7 working days.


alias

NCA,CEAL,CD66c,NCA-50/90,Carcinoembryonic antigen-related cell adhesion molecule 6


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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