Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Protein

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Description
Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) |
Host | Mammalian cells |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 48.03 kDa Sequence Fragment: Met1-Gly428 Tag: C-terminal His tag |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, SDS-PAGE |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | P13688 |
Alias | BGP,BGP1,BGPI,BGP-1,CD66a,Carcinoembryonic antigen-related cell adhesion molecule 1 |
Background | Protein CEACAM1 |
Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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CEACAM1 Antibody is a Rabbit Polyclonal antibody against CEACAM1. This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
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