Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Protein

Background

CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is a member of the CEA (carcinoembryonic antigen) family within the immunoglobulin superfamily (IgSF). This molecule plays a central role in intercellular adhesion, immune regulation, and tumor biology. CEACAM1 is highly expressed on various cell types, including epithelial cells, endothelial cells, leukocytes, and certain tumor cells. It is also involved in diverse physiological processes such as cellular differentiation, proliferation, angiogenesis, and immune response modulation. CEACAM1's expression is tightly regulated, often seen in specific tissues such as the liver, kidneys, and lungs, and it is known to be upregulated during certain immune responses and pathological conditions like inflammation and cancer. This protein has become a subject of interest due to its diverse biological functions, particularly in immune regulation and its role in tumor suppression or tumor progression, depending on the cellular context.