Human Cadherin-8 (CDH8) Protein
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Description
Cadherin-8 (CDH8) protein is a recombinant Human protein expressed in HEK293 cells.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cadherin-8 (CDH8) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Ala30-Met621 Tag: C-terminal 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 66.1 kDa Observed MW (SDS-PAGE): 89 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM PBS,150 mM NaCl,pH 7.4, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P55286 |
| Gene ID | 1006 |
| OMIM | 603008 |
| Background | Protein CDH8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
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Cadherin 8 (CDH8) Antibody
CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
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