Human C-Type Lectin Domain Family 4 Member M (CLEC4M) Protein

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Description
Human C-Type Lectin Domain Family 4 Member M (CLEC4M) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | C-Type Lectin Domain Family 4 Member M (CLEC4M) |
Host | Mammalian cells |
Origin | Human |
Observed MW | Molecular Weight: Calculated MW: 64.83 kDa Sequence Fragment: Ser78-Glu399 Tag: N-terminal Fc tag |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, SDS-PAGE |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | Q9H2X3 |
Alias | C-type lectin domain family 4 member M,CD299,LSIGN,CD209L,L-SIGN,DCSIGNR,HP10347,DC-SIGN2,DC-SIGNR,DC-SIGN-related protein,Dendritic cell-specific ICAM-3-grabbing non-integrin 2 |
Background | Protein CLEC4M |
Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Human CLEC4M (C-type lectin domain family 4 member M) ELISA Kit
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CLEC4M antibody
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus(PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus(PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1(PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E(PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5(PubMed:12433371). Acts as an attachment receptor for influenzavirus(PubMed:21191006). Acts as an attachment receptor for SARS coronavirus(PubMed:15479853). Acts as an attachment receptor for west-nile virus(PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus(PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein(PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule(PubMed:21203928).
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