Human C-Type Lectin Domain Family 4 Member K (CD207) Protein

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Description
Human C-Type Lectin Domain Family 4 Member K (CD207) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | C-Type Lectin Domain Family 4 Member K (CD207) |
Host | Mammalian cells |
Origin | Human |
Observed MW | Molecular Weight: Calculated MW: 33.14 kDa Sequence Fragment: Pro65-Pro328 Tag: C-terminal His tag |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized Reconstitute in sterile water to produce a stock solution. |
Tested Applications | ELISA, WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | Q9UJ71 |
Alias | C-type lectin domain family 4 member K,CLEC4K,Langerin |
Background | Protein CD207 |
Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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CD207 Antibody is a Rabbit Polyclonal antibody against CD207. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
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