Human C-Type Lectin Domain Family 4 Member K (CD207) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human C-Type Lectin Domain Family 4 Member K (CD207) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human C-type Lectin Domain Family 4 Member K (CD207) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | C-Type Lectin Domain Family 4 Member K (CD207) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UJ71 |
| Gene ID | 50489 |
| OMIM | 604862 |
| Alias | C-type lectin domain family 4 member K,CLEC4K,Langerin |
| Background | Elisa kits for CD207 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD207, commonly referred to as langerin, is a C-type lectin receptor primarily expressed in Langerhans cells (LCs), a specialized subset of dendritic cells residing in the epidermis and other epithelial surfaces, such as the respiratory and digestive tracts. CD207 plays a critical role in immune surveillance by recognizing and binding to specific carbohydrate structures on pathogens, facilitating their capture and internalization. This receptor is crucial for pathogen recognition and uptake, which supports the initiation of adaptive immune responses. Encoded by the CD207 gene, CD207 is instrumental in the function and identity of Langerhans cells. It is also the defining marker for Langerhans cells, distinguishing them from other dendritic cell subsets. Langerhans cells use CD207 to capture and internalize pathogens, leading to antigen processing and subsequent presentation to T cells, which is central to adaptive immunity. CD207’s unique feature is its ability to induce the formation of Birbeck granules—distinctive organelles with a rod and vesicle shape that are exclusive to Langerhans cells. These granules are believed to support the specialized antigen-processing function of CD207.
Related Products
C-type Lectin Domain Family 4 Member K (CD207) Antibody
CD207 Antibody is a Rabbit Polyclonal antibody against CD207. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Ver Producto
C-type Lectin Domain Family 4 Member K (CD207) Antibody
Cd207 Molecule, Langerin Antibody is a Rabbit Polyclonal antibody against Cd207 Molecule, Langerin.
Ver ProductoC-type Lectin Domain Family 4 Member K (CD207) Antibody
CD207 Antibody is a Rabbit Polyclonal against CD207.
Ver Producto