Human Butyrophilin Subfamily 3 Member A2 (BTN3A2) Protein

Este producto es parte de BTN3A - butyrophilin subfamily 3 member A
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338€ (10 µg)

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935106861
info@markelab.com
name
Human Butyrophilin Subfamily 3 Member A2 (BTN3A2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690460
tested applications
SDS-PAGE

Description

Human Butyrophilin 3A2 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Butyrophilin subfamily 3 member A2 is produced by our Mammalian expression system and the target gene encoding Gln30-Trp248 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Butyrophilin 3A2
Host
Human
Origin
Human
Observed MW
Molecular Weight: 24.6 kDa
Sequence Fragment: Gln30-Trp248
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
20mM PB, 150mM NaCl, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
P78410
Alias
BTF4,BT3.2,CD277,BTN3.2
Background
Protein BTN3A2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Butyrophilin subfamily 3 member A2 (BTN3A2) is a protein belonging to the butyrophilin family, which is part of the immunoglobulin superfamily. BTN3A2 is widely expressed in various tissues and is primarily involved in modulating immune responses, particularly through its interactions with immune cells. It plays a key role in regulating T-cell activation and proliferation by acting as a co-stimulatory or inhibitory molecule in immune signaling pathways. This protein is also implicated in the regulation of γδ T cells, which are critical for tumor surveillance and immune responses at epithelial barriers. BTN3A2 is structurally characterized by extracellular immunoglobulin-like domains, a transmembrane region, and an intracellular signaling domain. Its expression is often upregulated in response to inflammatory stimuli, making it an area of interest in autoimmune disorders and cancer immunotherapy. Recent studies suggest that BTN3A2 may have a role in modulating responses to microbial infections and maintaining immune homeostasis, highlighting its potential as a therapeutic target. Further research is needed to clarify its molecular interactions and pathways, particularly in the context of disease pathogenesis and immune modulation.
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