Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) ELISA Kit
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Description
Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q02742 |
| Gene ID | 2650 |
| OMIM | 600391 |
| Alias | G6NT,C2GNT,C2GNT1,NACGT2,NAGCT2,C2GNT-L,C2GlcNAcT |
| Background | Elisa kits for GCNT1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glucosaminyl (N-acetyl) transferase 1 (GCNT1) is a glycosyltransferase that catalyzes the addition of N-acetylglucosamine to mucin-type O-glycans, forming core 2 and core 4 branched structures critical for glycoprotein biosynthesis GCNT1 plays a key role in the synthesis of mucins, which protect epithelial barriers in the gastrointestinal and respiratory tracts by regulating mucus production and cell adhesion It is expressed in various tissues, particularly those with high mucus turnover, and is vital for immune responses and cellular signaling Dysregulation of GCNT1 has been associated with cancer progression, especially in breast and gastrointestinal cancers, where aberrant glycosylation promotes tumor invasion and metastasis Additionally, GCNT1 contributes to inflammatory diseases, impacting immune cell trafficking and epithelial defense pathways Studies highlight its involvement in maintaining epithelial integrity and its therapeutic potential as a target for diseases characterized by disrupted glycosylation patterns
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