Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for BAG3
proveedor
Abbexareference
abx252067Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human BAG3 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
BAG cochaperone 3 (BAG3) is a member of the BAG family of cochaperones that interacts with heat shock proteins like HSP70 and HSP90 to regulate cellular protein folding, stress responses, and protein degradation BAG3 is essential for the proper function of the cell’s proteostasis network, contributing to the maintenance of protein quality under stress conditions It plays a significant role in the regulation of apoptosis, autophagy, and cell survival, particularly in response to oxidative stress and heat shock conditions BAG3 is involved in the stabilization of key survival proteins, making it important for promoting cell survival during cellular stress It also has a role in skeletal muscle function and heart tissue maintenance, where its dysregulation contributes to diseases such as cardiomyopathy and muscle wasting disorders BAG3 has been implicated in cancer, where its overexpression promotes tumor cell survival, resistance to chemotherapy, and metastasis Studies suggest that BAG3 influences cytoskeletal dynamics and cellular motility, making it a key factor in cell migration and tissue remodeling
Características del producto
category
ELISA Kits
immunogen target
Bcl2 Associated Athanogene 3 (BAG3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
BAG-3,BIS,CAIR-1,MFM6,Bcl-2-associated athanogene 3,Bcl-2-binding protein Bis,BAG family molecular chaperone regulator 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
BAG3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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