Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit

Este producto es parte de BAG - BAG cochaperone 1
Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit
715€ (96 tests)

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Name
Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx150783
Tested Applications
ELISA

Description

Human Bcl2 Associated Athanogene 3 (BAG3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Bcl2 Associated Athanogene 3 (BAG3) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Bcl2 Associated Athanogene 3 (BAG3)

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Bcl2 Associated Athanogene 3 (BAG3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
BAG-3,BIS,CAIR-1,MFM6,Bcl-2-associated athanogene 3,Bcl-2-binding protein Bis,BAG family molecular chaperone regulator 3
Background
Elisa Kits for: BAG3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

BAG cochaperone 3 (BAG3) is a member of the BAG family of cochaperones that interacts with heat shock proteins like HSP70 and HSP90 to regulate cellular protein folding, stress responses, and protein degradation BAG3 is essential for the proper function of the cell’s proteostasis network, contributing to the maintenance of protein quality under stress conditions It plays a significant role in the regulation of apoptosis, autophagy, and cell survival, particularly in response to oxidative stress and heat shock conditions BAG3 is involved in the stabilization of key survival proteins, making it important for promoting cell survival during cellular stress It also has a role in skeletal muscle function and heart tissue maintenance, where its dysregulation contributes to diseases such as cardiomyopathy and muscle wasting disorders BAG3 has been implicated in cancer, where its overexpression promotes tumor cell survival, resistance to chemotherapy, and metastasis Studies suggest that BAG3 influences cytoskeletal dynamics and cellular motility, making it a key factor in cell migration and tissue remodeling

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