Human Basal Cell Adhesion Molecule (BCAM) Protein
234€ (2 µg)
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935106861
info@markelab.com
name
Human Basal Cell Adhesion Molecule (BCAM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680186
tested applications
SDS-PAGE
Description
Human Basal Cell Adhesion Molecule (BCAM) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Basal Cell Adhesion Molecule (BCAM) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | Basal cell adhesion molecule,Lutheran blood group,AU,LU,B-CAM,CD239,MSK19,Auberger B antigen,B-CAM cell surface glycoprotein |
| Background | Protein BCAM |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Basal Cell Adhesion Molecule (BCAM), also known as Lu antigen or Lutheran antigen, is a type I membrane glycoprotein primarily expressed on the surface of erythrocytes (red blood cells) and other cell types, including endothelial cells and certain epithelial cells. BCAM belongs to the immunoglobulin superfamily of cell adhesion molecules (IgCAMs), which are involved in the adhesion between cells and the extracellular matrix. It is notably involved in the Lutheran blood group system, which plays an important role in blood transfusion medicine. BCAM is an important adhesion molecule that facilitates interactions between cells, as well as between cells and their extracellular matrix (ECM), thus contributing to tissue integrity and signaling processes. BCAM is critical in the endothelial cell junctions and erythrocyte adhesion to endothelial cells, thereby influencing processes like inflammation, vascular permeability, and cell migration. BCAM's expression on erythrocytes links it to important blood group antigens, which have clinical relevance in transfusion medicine, as well as in understanding the molecular mechanisms of various diseases, including autoimmune disorders, inflammatory diseases, and cancers.
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