Human B-Lymphocyte Antigen CD20 (MS4A1) Protein
234€ (1 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human B-Lymphocyte Antigen CD20 (MS4A1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680080
tested applications
SDS-PAGE
Description
Human B-Lymphocyte Antigen CD20 (MS4A1) Protein is a recombinant protein produced in Sf9, Insect cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | B-Lymphocyte Antigen CD20 (MS4A1) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 1 µg |
| Size 2 | 5 µg |
| Size 3 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | B1,S7,Bp35,CD20,FMC7,CVID5,LEU-16,B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1 |
| Background | Protein MS4A1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MS4A1, also known as CD20, is a membrane-bound protein that plays a key role in the regulation of B-cell development, activation, and differentiation. It is predominantly expressed on the surface of B lymphocytes from the pre-B cell stage through to the mature B cell stage, and its expression is lost once B cells differentiate into plasma cells. CD20 is widely studied for its role in both normal immune function and its involvement in a variety of B-cell-related diseases, including non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and autoimmune diseases. MS4A1 is a member of the membrane-spanning 4A (MS4A) family of proteins, which includes several proteins with similar structural features, although their specific functions may differ across cell types and tissues. CD20 has become a major therapeutic target, particularly in B-cell depletion therapies, due to its restricted expression pattern and its role in the immune response. The development of anti-CD20 monoclonal antibodies, such as rituximab, has revolutionized the treatment of B-cell malignancies and certain autoimmune conditions.
Related Products
Human MS4A1(B-lymphocyte antigen CD20) ELISA Kit
Ver Producto
Mouse CD20 (B-lymphocyte antigen CD20) ELISA Kit
Ver Producto
anti- CD20 antibody
CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells.
Ver Producto