Human B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150782
tested applications
ELISA
Description
Human B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of B-Cell Activation Factor Receptor (BAFFR)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Tumor necrosis factor receptor superfamily member 13C,BAFFR,CD268,CVID4,BAFF-R,BROMIX,prolixin,B-cell-activating factor receptor,BAFF receptor,BAFF-R |
| Background | Elisa Kits for: TNFRSF13C |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
TNFRSF13C, also known as the B-cell activating factor receptor (BAFF-R), is a critical receptor involved in the regulation of B cell survival and maturation within the immune system. It belongs to the tumor necrosis factor receptor superfamily (TNFRSF), with BAFF-R specifically binding BAFF (B-cell activating factor), also known as TNFSF13B. BAFF-R signaling is essential for the differentiation of B cells and their progression through developmental stages, playing a crucial role in both innate and adaptive immunity. Dysfunction in TNFRSF13C signaling has been implicated in immune-related disorders, including autoimmune diseases and immunodeficiencies. Genetic mutations or dysregulation in BAFF-R and BAFF signaling pathways are associated with conditions such as Systemic Lupus Erythematosus (SLE) and Common Variable Immunodeficiency (CVID), as they can lead to abnormal B cell activity, autoreactivity, and altered antibody production. This receptor is also studied as a therapeutic target for autoimmune diseases, with strategies aimed at modulating BAFF levels to control B cell activity.
Related Products
Human TNFRSF13C/BAFFR (Tumor necrosis factor receptor superfamily member 13C) ELISA Kit
Ver Producto
Mouse TNFRSF13C/BAFFR (B-Cell Activation Factor Receptor) ELISA Kit
Ver Producto