Human ATP Binding Cassette Subfamily G Member 1 (ABCG1) ELISA Kit
689€ (96 tests)
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935106861
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name
Human ATP Binding Cassette Subfamily G Member 1 (ABCG1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150512
tested applications
ELISA
Description
Human ATP Binding Cassette Subfamily G Member 1 (ABCG1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Subfamily G Member 1 (ABCG1) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ATP Binding Cassette Transporter G1 (ABCG1)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP Binding Cassette Subfamily G Member 1 (ABCG1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | BCC7,BMFS5,LFS1,P53,TRP53,ABC8, WHITE1 |
| Background | Elisa kits for ABCG1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCG1 is a transmembrane ATP-binding cassette transporter that plays a critical role in cellular cholesterol and lipid homeostasis. It is primarily involved in the efflux of cholesterol and phospholipids to high-density lipoprotein (HDL) particles, facilitating reverse cholesterol transport and preventing intracellular lipid accumulation. ABCG1 is ubiquitously expressed but is most active in macrophages, endothelial cells, and the liver, where it regulates cholesterol levels and protects cells from lipid toxicity. Structurally, ABCG1 contains nucleotide-binding domains that hydrolyze ATP to drive lipid transport across membranes. Dysregulation of ABCG1 expression has been implicated in atherosclerosis, as impaired cholesterol efflux can lead to foam cell formation in arterial walls. ABCG1 is also involved in modulating inflammation and oxidative stress, highlighting its protective role in cardiovascular health. Furthermore, ABCG1 expression is influenced by nuclear receptors such as LXR (liver X receptor), which coordinate lipid metabolism and inflammatory responses, underscoring its importance in lipid regulatory networks and metabolic diseases.
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