Human ATP-binding cassette sub-family G member 5 (ABCG5) ELISA Kit
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Description
Human ATP-binding cassette sub-family G member 5 (ABCG5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP-binding cassette sub-family G member 5 (ABCG5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP-binding cassette sub-family G member 5 (ABCG5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9H222 |
| Alias | STSL,STSL2,Sterolin 1 |
| Background | Elisa kits for ABCG5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCG5 is an integral membrane protein and part of the ATP-binding cassette (ABC) transporter family, specifically subfamily G. Expressed primarily in the liver and intestines, ABCG5 works in tandem with ABCG8 to regulate dietary sterol absorption and biliary sterol excretion. It plays a vital role in maintaining cholesterol and plant sterol homeostasis. Mutations in ABCG5 are linked to sitosterolemia, a rare autosomal recessive disorder characterized by hyperabsorption of plant sterols and cholesterol. Its function is essential for reducing sterol accumulation and preventing cardiovascular diseases.
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ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
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ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
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