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Human Aryl Hydrocarbon Receptor Interacting Protein (AIP) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits AIP
proveedor
Abbexareference
abx384602Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Aryl Hydrocarbon Receptor Interacting Protein (AIP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aryl Hydrocarbon Receptor Interacting Protein (AIP) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The Aryl-hydrocarbon-interacting protein (AIP), also known as aryl hydrocarbon receptor-interacting protein, is a cellular protein that interacts with the aryl hydrocarbon receptor (AhR). AhR is a ligand-activated transcription factor that plays a crucial role in the regulation of gene expression in response to environmental toxins, such as dioxins, polycyclic aromatic hydrocarbons (PAHs), and other xenobiotics. AIP acts as a chaperone protein for AhR, assisting in its proper folding, stabilization, and nuclear translocation upon ligand binding. Through its interaction with AhR, AIP regulates the transcriptional activity of AhR-dependent genes involved in xenobiotic metabolism, detoxification, and other cellular processes. Mutations in the AIP gene are associated with a rare hereditary condition known as familial isolated pituitary adenoma (FIPA). Individuals with FIPA develop benign tumors of the pituitary gland, which can lead to hormonal imbalances and various health issues. These mutations disrupt the normal function of AIP, impairing its ability to interact with AhR and regulate its activity effectively.
Características del producto
category
ELISA Kits
immunogen target
Aryl Hydrocarbon Receptor Interacting Protein (AIP)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ARA9,FKBP16,FKBP37,PITA1,SMTPHN,XAP-2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
AIP
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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