Human Arginase 1 (ARG1) Protein (Active)

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338€ (10 µg)

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935106861
info@markelab.com
name
Human Arginase 1 (ARG1) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx690208
tested applications
SDS-PAGE

Description

Human Arginase-1 Protein is a recombinant protein from Human produced in E. coli. Recombinant Human Arginase-1 is produced by our E.coli expression system and the target gene encoding Met1-lys322 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Arginase-1
Host
E. coli
Origin
Human
Observed MW
Molecular Weight: 35.8 kDa

Sequence Fragment: Met1-Lys322

Tag: C-terminal 6 His tag

Validity: The validity for this protein is 6 months.
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Tested Applications
SDS-PAGE
Buffer
20mM Tris, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at < -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P05089
Background
Protein ARG1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

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