Human Arginase 1 (ARG1) Protein

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Description
Arginase 1 (ARG1) Protein is a recombinant protein produced in E. coli.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Arginase 1 (ARG1) |
Host | E. coli |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Origin | Human |
Expression | Recombinant |
Purity | > 85% (SDS-PAGE) |
Size 1 | 5 µg |
Size 2 | 25 µg |
Size 3 | 1 mg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P05089 |
Background | Protein ARG1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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ARG1 antibody
Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
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