Human Apolipoprotein M (APOM) Protein

Este producto es parte de APOM - Apolipoprotein M
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234€ (2 µg)

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935106861
info@markelab.com
name
Human Apolipoprotein M (APOM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262404
tested applications
SDS-PAGE

Description

Apolipoprotein-M Protein is a recombinant cytokine.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
APOM
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
O95445
Alias
APOM, G3a, HSPC336, NG20, apo-M, apolipoprotein M
Background
Protein APOM
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Apolipoprotein M (APOM) is a member of the apolipoprotein family primarily involved in lipid transport and metabolism. APOM is predominantly expressed in the liver and kidneys and is secreted into the plasma, where it associates mainly with high-density lipoprotein (HDL) particles. APOM plays a key role in lipid homeostasis by transporting sphingosine-1-phosphate (S1P), a bioactive lipid mediator involved in immune response, vascular development, and endothelial barrier integrity. APOM also enhances the anti-inflammatory and antioxidant properties of HDL, contributing to its atheroprotective function in cardiovascular health. Recent studies suggest that APOM regulates the S1P signaling pathway, which is crucial for lymphocyte trafficking, vascular permeability, and cell survival. Altered APOM levels have been observed in metabolic disorders such as type 2 diabetes, atherosclerosis, and cardiovascular disease, highlighting its role as a biomarker and potential therapeutic target. Its involvement in the modulation of endothelial function, cholesterol efflux, and immune regulation underscores APOM's critical role in maintaining cardiovascular and metabolic homeostasis. Ongoing research aims to explore APOM’s therapeutic potential, particularly in improving HDL functionality and S1P-based signaling for cardiovascular disease prevention.

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