Human Apolipoprotein F (APOF) ELISA Kit
689€ (96 tests)
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name
Human Apolipoprotein F (APOF) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150718
tested applications
ELISA
Description
Human Apolipoprotein F (APOF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apolipoprotein F (APOF) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Apolipoprotein F (APOF)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Apolipoprotein F (APOF) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.94 ng/ml - 60 ng/ml |
| Sensitivity | < 0.37 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | APOF, Apo-F, LTIP, apolipoprotein F,Apo F |
| Background | Elisa kits for APOF |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Apolipoprotein F (APOF) is a lesser-known but essential component of the apolipoprotein family, predominantly found in high-density lipoproteins (HDL) and low-density lipoproteins (LDL). ApoF plays a regulatory role in cholesteryl ester transfer protein (CETP) activity, which facilitates the transfer of cholesteryl esters from HDL to triglyceride-rich lipoproteins like VLDL and LDL. By modulating CETP activity, ApoF influences cholesterol distribution, lipid metabolism, and the balance between HDL and LDL particles. ApoF is mainly synthesized in the liver and circulates in plasma, with elevated levels observed in dyslipidemia and cardiovascular diseases. ApoF is thought to act as a negative regulator of CETP, reducing cholesterol transfer and preserving HDL levels, which are vital for reverse cholesterol transport and cardiovascular health. Its role in maintaining HDL function positions ApoF as a potential therapeutic target in atherosclerosis and other metabolic disorders. Further research is exploring its contribution to lipid homeostasis, inflammation, and cholesterol efflux pathways, which are critical for combating cardiovascular disease and lipid-related pathologies.
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Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein(CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
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