Human Apolipoprotein D (APOD) Protein

Este producto es parte de APOD - Apolipoprotein D
Human Apolipoprotein D (APOD) Protein
403€ (2 µg)

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Name
Human Apolipoprotein D (APOD) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx263521

Description

APO-D GST Tag Protein is a recombinant cytokine.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
APOD
Assay Type
Activity: Not tested
Tag: GST tag
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Size 1
2 µg
Size 2
5 µg
Size 3
10 µg
Form
Liquid
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P05090
Alias
APOD, Apod, apolipoprotein D
Background
Protein APOD
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Apolipoprotein D (APOD) is a unique member of the apolipoprotein family, functioning as a lipid transporter in the plasma and extracellular fluids. Unlike other apolipoproteins, APOD is not synthesized in the liver but is predominantly produced in the central nervous system (CNS), liver, kidneys, and mammary glands. APOD associates with high-density lipoprotein (HDL) and contributes to cholesterol transport, as well as lipid metabolism. Structurally, APOD is classified as a member of the lipocalin family, which binds small hydrophobic molecules, such as arachidonic acid and cholesterol. It has a prominent role in antioxidant defense by neutralizing reactive oxygen species (ROS) and reducing oxidative stress, particularly in the CNS. APOD is upregulated during injury and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, and stroke, indicating its neuroprotective function. Elevated levels of APOD are also found in cancer, cardiovascular disease, and diabetes, suggesting its role in cellular stress responses. APOD may regulate inflammation, cellular lipid homeostasis, and signal transduction, making it a promising biomarker and therapeutic target in age-related disorders, metabolic syndromes, and neurological diseases.

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