Human Apolipoprotein AI Protein
611€ (1 mg)
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name
Human Apolipoprotein AI Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx060867
Description
Human Apolipoprotein AI Protein is a purified lipoprotein. This protein is from Human Plasma HDL.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Human Apolipo AI |
| Host | Human |
| Origin | Human |
| Conjugation | Unconjugated |
| Purification | Purified from Human Plasma HDL |
| Size 1 | 1 mg |
| Form | Liquid |
| Buffer | Buffer contains NaN3 as a preservative. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI |
| Background | Protein APOA1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.
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