Human Apolipoprotein A1 (APOA1) Protein

Este producto es parte de APOA1 - Apolipoprotein A1
Human Apolipoprotein A1 (APOA1) Protein

Pida mas información

935106861

info@markelab.com

Precio

481€ (20 µg)

Protein APOA1

proveedor

Abbexa

reference

abx694139

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Apolipoprotein A1 (APOA1) Protein is a recombinant Human protein expressed in HEK293 cells.

Background

APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.

Características del producto

category

Proteins and Peptides

origin

Human

host

HEK293 cells

host

HEK293 cells

form

Lyophilized Reconstitute in sterile H2O. Do not vortex.

tested applications

SDS-PAGE

size 1

20 µg

size 2

100 µg

observerd MW

Molecular Weight: Calculated MW: 29.26 kDa Observed MW (SDS-PAGE): 30 kDa Sequence Fragment: Met1-Gln267 Tag: C-terminal His tag

expression

Recombinant

purity

>95% (SDS-PAGE)

buffer

Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.

storage

Store lyophilized between -20 °C and -80 °C.

or code

APOA1

dry ice

No

availability

Shipped within 5-15 working days.

alias

Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI

uniprot id

https://www.uniprot.org/uniprotkb/P02647

gene id

https://www.ncbi.nlm.nih.gov/gene/335

NCBI accession

NP_3.1

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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