Human Apolipoprotein A1 (APOA1) Protein
377€ (500 µg)
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name
Human Apolipoprotein A1 (APOA1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx670007
tested applications
ELISA
Description
Human Apolipoprotein A-I (APOA1) Protein is a Native protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apolipoprotein A1 (APOA1) |
| Host | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Size 1 | 500 µg |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Buffer | Prior to lyophilization: 0.05 M Sodium chloride, 0.01 M Sodium carbonate |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C after reconstitution. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P02647 |
| Alias | Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI |
| Background | Protein APOA1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.
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