Human Antigen-Presenting Glycoprotein CD1d (CD1D) ELISA Kit
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Description
Human Antigen-Presenting Glycoprotein CD1d (CD1D) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Antigen-Presenting Glycoprotein CD1d (CD1D) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Antigen-Presenting Glycoprotein CD1d (CD1D) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P15813 |
| Gene ID | 912 |
| OMIM | 188410 |
| Alias | R3,CD1A,R3G1,Antigen-presenting glycoprotein CD1d |
| Background | Elisa kits for CD1D |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD1D is a key member of the CD1 family of glycoproteins, which are specialized antigen-presenting molecules. CD1 proteins are distinct from classical major histocompatibility complex (MHC) class I and II molecules in that they present lipid and glycolipid antigens, rather than peptide antigens, to T cells. CD1D is unique within the CD1 family because of its specialized role in presenting lipid antigens to natural killer T (NKT) cells, particularly the invariant NKT (iNKT) cells, which express a semi-invariant T cell receptor (TCR). This interaction is essential for initiating rapid immune responses against a variety of pathogens, as well as in immune regulation. CD1D is expressed predominantly on antigen-presenting cells (APCs), such as dendritic cells, macrophages, and B cells, but is also found on certain epithelial cells. Through its interaction with NKT cells, CD1D mediates a range of immune responses, including the production of cytokines that regulate the function of other immune cells, such as dendritic cells, natural killer (NK) cells, and conventional T cells. This makes CD1D important not only for pathogen defense but also for the regulation of inflammation, tolerance, and tumor immunity.
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