Human Muellerian-Inhibiting Factor (AMH) Protein
Pida mas información
935106861
info@markelab.com
Precio
247€ (10 µg)
Protein AMH
proveedor
Abbexareference
abx652086Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Muellerian-Inhibiting Factor (AMH) Protein is a recombinant Human protein expressed in E. coli.
Background
Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting factor (MIF), is a protein hormone that plays a critical role in the development of the reproductive system, particularly in males. It is produced by cells within the testes called Sertoli cells, as well as by granulosa cells in the ovaries of females. During fetal development in males, AMH is secreted by the Sertoli cells and functions to inhibit the development of the Müllerian ducts, which are precursor structures for female reproductive organs such as the fallopian tubes, uterus, and upper vagina. By suppressing the development of these Müllerian structures, AMH helps promote the formation of male reproductive organs, including the epididymis, vas deferens, and seminal vesicles. In females, AMH is also produced by granulosa cells within ovarian follicles, but its role is different. In females, AMH levels are highest during early follicular development and decline as follicles mature. AMH is involved in regulating the growth and development of ovarian follicles and has been used as a marker of ovarian reserve, which refers to the number and quality of a woman's remaining eggs
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Muellerian-Inhibiting Factor (AMH)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 44.3 kDa Observed MW (SDS-PAGE): 48 kDa Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed. Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Thr193-Arg560 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AMH
dry ice
No
availability
Shipped within 5-7 working days.
alias
AMH,MIF
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human AMH(Muellerian-inhibiting factor) ELISA Kit
proveedor
FineTestreference
EH0528reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Amh(Muellerian-inhibiting factor) ELISA Kit
proveedor
FineTestreference
EM0356reactivity
mousestatus
RUOPrecio a consultar
Ver másRat AMH(anti-Mullerian hormone) ELISA kit
proveedor
FineTestreference
ER1941reactivity
ratstatus
RUOPrecio a consultar
Ver más