Human Muellerian-Inhibiting Factor (AMH) Protein
247€ (10 µg)
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935106861
info@markelab.com
name
Human Muellerian-Inhibiting Factor (AMH) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065389
tested applications
WB, SDS-PAGE
Description
Human AMH is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Muellerian-Inhibiting Factor (AMH) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 12.8 kDa Observed MW (SDS-PAGE): 14 kDa Concentration: Prior to lyophilization: 100 µg/ml Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P03971 |
| Alias | AMH,MIF |
| Background | Protein AMH |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting factor (MIF), is a protein hormone that plays a critical role in the development of the reproductive system, particularly in males. It is produced by cells within the testes called Sertoli cells, as well as by granulosa cells in the ovaries of females. During fetal development in males, AMH is secreted by the Sertoli cells and functions to inhibit the development of the Müllerian ducts, which are precursor structures for female reproductive organs such as the fallopian tubes, uterus, and upper vagina. By suppressing the development of these Müllerian structures, AMH helps promote the formation of male reproductive organs, including the epididymis, vas deferens, and seminal vesicles. In females, AMH is also produced by granulosa cells within ovarian follicles, but its role is different. In females, AMH levels are highest during early follicular development and decline as follicles mature. AMH is involved in regulating the growth and development of ovarian follicles and has been used as a marker of ovarian reserve, which refers to the number and quality of a woman's remaining eggs
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